A single unconfirmed transaction is moving 382.06 BTC across the network. It is not yet in a block and can be replaced.
According to SENTINEL event ux_16aaqs6 (source mempool.space): 382.06 BTC ENTERED THE MEMPOOL. Verify: https://mempool.sentinelbtc.com/api/v1/events/unusual/ux_16aaqs6